The authors of the Prescrire International review referenced a case of a year-old man who had severe heartburn. He was diagnosed with severe gastroesophageal reflux disease. His doctor prescribed the proton pump inhibitor omeprazole twice daily. The omeprazole tablets were crushed before being administered via a tube placed in his stomach.
Crushing the tablets likely compromised the integrity of their coating, allowing the stomach acid to inactivate the omeprazole, thus rendering the drug ineffective. Omeprazole also is available over the counter OTC. Finally, the authors of the Prescrire International review reported that some medications have a coating that is intended to prevent the active ingredients from causing ulcers and tissue injury in the mouth, stomach or intestines.
For example, crushing certain iron supplements available in tablet form can cause ulcers in the mouth due to exposure to the iron. When taking a prescription drug, you should never crush a tablet, open a capsule or chew either without first asking the prescribing health care provider or dispensing pharmacist whether it is safe to do so. Carefully adhere to such instructions. If you are experiencing difficulty swallowing tablets or capsules and are taking a prescription drug that is unsafe to crush, chew or open, consult the prescribing health care professional about other treatment options.
There may be a liquid formulation of the same drug. There also may be a smaller tablet or capsule form of the same drug or another drug that you can swallow or that can be safely crushed or opened before ingesting.
Prescrire Intl. September ;23 March Accessed March 14, September Accessed November 25, Fatality from administration of labetalol and crushed extended-release nifedipine. Cutting, crushing, chewing, opening, or dissolving medicines. March 7, Protecting Democracy [1] American democracy is in jeopardy, from the disastrous Citizens United ruling that flooded our politics with corporate cash to the immoral assault on voting rights.
Get Corporate Money Out of Politics. Fight Pharma Greed. Win Medicare for All. Our Mission. Climate Roadmap for U. Subscribe to the Supreme Court Conference Preview. Share Facebook Twitter Email. Stay Updated on Public Citizen. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:.
However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you.
Certain symptoms may indicate that your dosage of digoxin is too high. Call your doctor if you experience:. These include:. If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal cause death. It may make your ventricular fibrillation worse. Digoxin may increase your risk even further.
For people with sinus node disease and AV block: Digoxin can cause severe low heart rate and complete heart block if you have sinus node disease or atrioventricular AV block. If you have sinus node disease or AV block, you should get a pacemaker before starting digoxin.
For people with preserved left ventricular systolic function: If you have this type of heart failure, you should not use digoxin. It may increase your risk of side effects, such as chest pain and shortness of breath. This is done to prevent heart rhythm problems.
Using this drug can restrict blood flow to the heart. It can narrow your blood vessels and cause inflammation. For people with kidney disease: Digoxin is cleared from your body by your kidneys. Your digoxin dosage should be decreased if you have kidney problems. For people with hypothyroidism: You might be more sensitive to digoxin. Because of this, your dosage of digoxin may need to be reduced.
For people with electrolyte imbalances: If you have low potassium levels, digoxin may be more active in your body, increasing your risk of dangerous side effects. For pregnant women: Digoxin is a category C pregnancy drug.
Digoxin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. For women who are breastfeeding: Studies have shown that digoxin passes through breast milk.
For seniors: Seniors may need smaller doses of digoxin and may be monitored more closely. Adults over 65 years old are more likely to have kidney problems, which may lead to greater drug side effects. However, the drug may still be used to treat heart failure in children. Digoxin oral tablet is used for long-term treatment. For this drug to work well, a certain amount needs to be in your body at all times.
If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug in adults and children can include:. But if your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose.
Never try to catch up by taking two doses at once. This could result in dangerous side effects. How to tell the drug is working: Your heart rate should return to normal or your symptoms should get better. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.
There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication.
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Film-coated Note: active ingredients are surrounded by wax matrix to prevent healthcare exposure; women who are, or may become, pregnant should not handle crushed or broken tablet.
Empty contents into a spoon for administration. Do not swallow the capsule. Do not chew or crush the contents of the capsule. Mucous membrane irritant; Note: accidentally opened or damaged capsules require rigorous precautions to avoid inhalation or contact with the skin or mucous membranes i.
Slow-release; Note: crushing, chewing, or dissolving capsules can cause rapid release and absorption of a potentially fatal dose. Note: irritant; avoid contact with skin or mucous membranes; avoid contact with crushed or broken tablets. Add to cart. AcipHex rabeprazole Tablet Slow-release AcipHex Sprinkle rabeprazole Capsule Slow-release; Note: contents are intended to be sprinkled on food or liquid but should not be chewed or crushed.
Acticlate doxycycline hyclate Capsule; Tablet Film-coated; tablet is scored and may be split; Note: mg tablets can be broken into two-thirds or one-third to provide a mg and 50 mg strength, respectively Actiq fenta NYL Lozenge Slow-release; Note: this lollipop delivery system requires the patient to slowly allow dissolution.
Actonel risedronate Tablet Irritant; Note: chewed, crushed, or sucked tablets may cause oropharyngeal ulceration. Copiktra develisib Capsule Antineoplastic Coreg CR carvedilol Capsule Slow-release a Note: may add contents of capsule to chilled, not warm, applesauce and consume immediately Cotempla XR-ODT methylphenidate Tablet Slow-release; oral disintegrating tablet designed to disintegrate on the tongue. Creon 5, 10, 20 pancrelipase Capsule Slow-release a Cresemba isavuconazium Capsule - Crixivan indinavir Capsule Taste; Note: capsule may be opened and mixed with fruit puree e.
List of Confused Drug Names. Medications requiring special safeguards to reduce the risk of errors and minimize harm.
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